Stephen D. Johnston
Cellular & Molecular Biology
Associate Professor (1999) and Department Chair
Roger & Nadeane Hruby Professor in the Liberal Arts & Sciences
BS, Iowa State Univ. (1990) MS, Iowa State Univ. (1991) PhD, Univ. of Wisconsin (1996) Post-doctoral research, Univ. of Minnesota (1996-1999)
Teaching: |
Cell biology, Molecular Biology, Biology II |
Research: |
Msi1: Signal transduction and chromatin assembly in Saccharomyces cerevisiae |
Publications: |
Pratt, Z. L.*, B. J. Drehman, M. E. Miller, and S. D. Johnston. 2007. Mutual interdependence of MSI1 (CAC3) and YAK1 in Saccharomyces cerevisiae. J. Mol. Biol. 368:30-43.
Johnston, S. D., S. Enomoto, L. Schneper, M. C. McClellan, F. Twu*, N. D. Montgomery*, S. A. Haney, J. R. Broach, and J. Berman. 2001. CAC3 (MSI1) suppression of RAS2-G19V is independent of chromatin assembly factor I and mediated by NPR1. Mol. Cell. Biol. 21:1784-1794.
Enomoto, S., S. D. Johnston, and J. Berman. 2000. Identification of a novel allele of SIR3 defective in the maintenance, but not the establishment, of silencing in Saccharomyces cerevisiae. Genetics 155:523-538.
Asleson, C. M., J. C. Asleson, E. Malandra, S. D. Johnston, and J. Berman. 2000. Filamentous growth of S. cerevisiae is regulated by extracellular manganese concentration. Fungal Genetics and Biology 30:155-162.
Johnston, S. D., J. E. Lew, and J. Berman. 1999. Gbp1p, a protein with RNA recognition motifs, binds single-stranded telomeric DNA and changes its binding specificity upon dimerization. Mol. Cell. Biol., 19:923-933.
Qian, Z., H. Huang, J. Y. Hong, C. L. Burck, S. D. Johnston, J. Berman, A. Carol, and S. W. Liebman. 1998. Yeast Ty1 retrotransposition is stimulated by a synergistic interaction between mutations in chromatin assembly factor I and histone regulatory proteins. Mol. Cell. Biol., 18:4783-4792.
Johnston, S. D., X. Liu, F. Zuo, T. L. Eisenbraun, S. R. Wiley, R. J. Kraus, and J. E. Mertz. 1997. Estrogen-related receptor a1 functionally binds as a monomer to extended half-site sequences including ones contained within estrogen-response elements. Mol. Endocrinol. 11:342-352.
Johnston, S. D., X.-M. Yu, and J. E. Mertz. 1996. The major transcriptional transactivation domain of simian virus 40 large T antigen associates nonconcurrently with multiple components of the transcriptional preinitiation complex. J. Virol. 70:1191-1202.
Boettcher, P. J., A. E. Freeman, S. D. Johnston, R. K. Smith, D. C. Beitz, and B. T. McDaniel. 1996. Relationships between polymorphism for mitochondrial deoxyribonucleic acid and yield traits of Holstein cows. Journal of Dairy Science, 79:647-654.
* indicates undergraduate student collaborators
External Funding: |
Merck/AAAS Undergraduate Science Research Program Grant: support for student stipends for interdisciplinary research in biology and chemistry, 2005-2008.
National Institutes of Health Academic Research Enhancement Award (NIH-AREA) from the National Institute of General Medical Sciences: "Regulation of the Multiple Functions of Msi1p/Cac3p," 2003-2006.